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p. 868. Nervous systemlocked

  • Lewis Wolpert

Abstract

The nervous system is the most complex of the organ systems in the animal embryo. ‘Nervous system’ shows that the nervous-system development can be divided into four major stages: the specification of neural cell identity; the outgrowth of axons to their targets; the formation of synapses with target cells, which can be other neurons, muscle or gland cells; and the refinement of synaptic connections through the elimination of axon branches and cell death. These stages are described with details of neuronal circuit formation and the links between sensory receptors, which receive signals from the outside world, and their targets in the brain that enable us to make sense of these signals.

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