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1. Biology: from analysis to synthesis

1. Biology: from analysis to synthesis  

Jamie A. Davies

in Synthetic Biology: A Very Short Introduction

Print Publication Year: 
Jul 2018
Published Online: 
Jul 2018
eISBN: 
9780191841699
DOI: 
10.1093/actrade/9780198803492.003.0001
Item type: 
chapter
ISBN: 
9780198803492
Synthetic biology—the creation of new living systems by design—is a rapidly growing area of science and technology that is attracting attention well beyond the laboratory and is provoking ... More
Conclusionthe varied concepts of the gene

Conclusion: the varied concepts of the gene  

Jonathan Slack

in Genes: A Very Short Introduction

Print Publication Year: 
Sep 2014
Published Online: 
Sep 2014
eISBN: 
9780191780950
DOI: 
10.1093/actrade/9780199676507.003.0007
Item type: 
chapter
ISBN: 
9780199676507
There are many concepts of the gene. They range from defined sequences of DNA encoding proteins, to variant genes distinguishing individuals (markers), to unknown genes controlling ... More
7. Creating life

7. Creating life  

Jamie A. Davies

in Synthetic Biology: A Very Short Introduction

Print Publication Year: 
Jul 2018
Published Online: 
Jul 2018
eISBN: 
9780191841699
DOI: 
10.1093/actrade/9780198803492.003.0007
Item type: 
chapter
ISBN: 
9780198803492
Synthetic biology has ‘two souls’, one focused on engineering new features into existing life, the other aiming to create life de novo. The goal of creating life is arguably far more ... More
8. Cultural impact

8. Cultural impact  

Jamie A. Davies

in Synthetic Biology: A Very Short Introduction

Print Publication Year: 
Jul 2018
Published Online: 
Jul 2018
eISBN: 
9780191841699
DOI: 
10.1093/actrade/9780198803492.003.0008
Item type: 
chapter
ISBN: 
9780198803492
Science is not an isolated enterprise: it is affected by and affects broader society and culture. Synthetic biology has changed aspects of education; stimulated artists, writers, and ... More
5. Evolutionary genomics

5. Evolutionary genomics  

John Archibald

in Genomics: A Very Short Introduction

Print Publication Year: 
Mar 2018
Published Online: 
Mar 2018
eISBN: 
9780191827877
DOI: 
10.1093/actrade/9780198786207.003.0005
Item type: 
chapter
ISBN: 
9780198786207
We are still learning how to make sense of what genome sequences have to tell us. ‘Evolutionary genomics’ first considers the ‘molecular clock’, a bedrock concept underlying modern ... More
7. The future of genomics

7. The future of genomics  

John Archibald

in Genomics: A Very Short Introduction

Print Publication Year: 
Mar 2018
Published Online: 
Mar 2018
eISBN: 
9780191827877
DOI: 
10.1093/actrade/9780198786207.003.0007
Item type: 
chapter
ISBN: 
9780198786207
‘The future of genomics’ explores some of the ways in which genome science will continue to expand the frontiers of human knowledge, as well as change our world and the way we interact with ... More
2. Genes as DNA

2. Genes as DNA  

Jonathan Slack

in Genes: A Very Short Introduction

Print Publication Year: 
Sep 2014
Published Online: 
Sep 2014
eISBN: 
9780191780950
DOI: 
10.1093/actrade/9780199676507.003.0002
Item type: 
chapter
ISBN: 
9780199676507
After 1944, a remarkable set of discoveries established the overall shape of modern molecular biology and most famous of all was the discovery of the three dimensional structure of DNA: the ... More
4. Genes as markers

4. Genes as markers  

Jonathan Slack

in Genes: A Very Short Introduction

Print Publication Year: 
Sep 2014
Published Online: 
Sep 2014
eISBN: 
9780191780950
DOI: 
10.1093/actrade/9780199676507.003.0004
Item type: 
chapter
ISBN: 
9780199676507
‘Genes as markers’ shows that most genetic variation does not affect gene function or activity, but it is still of enormous interest. Notably it enables the identification of individual ... More
1. Genes before 1944

1. Genes before 1944  

Jonathan Slack

in Genes: A Very Short Introduction

Print Publication Year: 
Sep 2014
Published Online: 
Sep 2014
eISBN: 
9780191780950
DOI: 
10.1093/actrade/9780199676507.003.0001
Item type: 
chapter
ISBN: 
9780199676507
‘Genes before 1944’ outlines the development in our understanding of genes based on Gregor Mendel’s work carried out in 1866 on hereditary factors, to Oswald Avery’s paper on the chemical ... More
6. Genes in evolution

6. Genes in evolution  

Jonathan Slack

in Genes: A Very Short Introduction

Print Publication Year: 
Sep 2014
Published Online: 
Sep 2014
eISBN: 
9780191780950
DOI: 
10.1093/actrade/9780199676507.003.0006
Item type: 
chapter
ISBN: 
9780199676507
‘Genes in evolution’ illustrates that a great deal of change in the primary sequence of DNA was not adaptive at all. It was not natural selection, but ‘neutral evolution’, consisting of an ... More
5. Genes of small effect

5. Genes of small effect  

Jonathan Slack

in Genes: A Very Short Introduction

Print Publication Year: 
Sep 2014
Published Online: 
Sep 2014
eISBN: 
9780191780950
DOI: 
10.1093/actrade/9780199676507.003.0005
Item type: 
chapter
ISBN: 
9780199676507
‘Genes of small effect’ considers unidentified genes whose variants collectively affect some characteristic of interest. Many aspects of living organisms depend not on the action of a few ... More
6. Genomics and the microbial world

6. Genomics and the microbial world  

John Archibald

in Genomics: A Very Short Introduction

Print Publication Year: 
Mar 2018
Published Online: 
Mar 2018
eISBN: 
9780191827877
DOI: 
10.1093/actrade/9780198786207.003.0006
Item type: 
chapter
ISBN: 
9780198786207
Together, molecular biology and genomics have made it possible to explore the diversity and ecology of the 99 per cent of microbes that cannot be cultured in laboratories. ‘Genomics and the ... More
5. Heredity in the 19th century

5. Heredity in the 19th century  

John Waller

in Heredity: A Very Short Introduction

Print Publication Year: 
Aug 2017
Published Online: 
Aug 2017
eISBN: 
9780191831706
DOI: 
10.1093/actrade/9780198790457.003.0005
Item type: 
chapter
ISBN: 
9780198790457
The 19th century stands out in the history of ideas about heredity both for the striking progress made in the biological sciences and for the intensity of the conflict between competing ... More
3. Heredity in the early modern world, 1450–1700

3. Heredity in the early modern world, 1450–1700  

John Waller

in Heredity: A Very Short Introduction

Print Publication Year: 
Aug 2017
Published Online: 
Aug 2017
eISBN: 
9780191831706
DOI: 
10.1093/actrade/9780198790457.003.0003
Item type: 
chapter
ISBN: 
9780198790457
‘Heredity in the early modern world, 1450–1700’ outlines several factors that gave the concept of inheritance a new salience during this period. First, a period of renewed excitement about ... More
4. Heredity in the Enlightenment

4. Heredity in the Enlightenment  

John Waller

in Heredity: A Very Short Introduction

Print Publication Year: 
Aug 2017
Published Online: 
Aug 2017
eISBN: 
9780191831706
DOI: 
10.1093/actrade/9780198790457.003.0004
Item type: 
chapter
ISBN: 
9780198790457
The concept of heredity came of age during the Enlightenment. Botanists and naturalists pioneered the systematic study of sex and inheritance; natural philosophers refined their ideas about ... More
2. How synthetic biology is done

2. How synthetic biology is done  

Jamie A. Davies

in Synthetic Biology: A Very Short Introduction

Print Publication Year: 
Jul 2018
Published Online: 
Jul 2018
eISBN: 
9780191841699
DOI: 
10.1093/actrade/9780198803492.003.0002
Item type: 
chapter
ISBN: 
9780198803492
Synthetic biology depends on technologies for reading and writing DNA sequences of genes. Modification is almost always done at the genetic level because genes are heritable, needing to be ... More
2. How to read the book of life

2. How to read the book of life  

John Archibald

in Genomics: A Very Short Introduction

Print Publication Year: 
Mar 2018
Published Online: 
Mar 2018
eISBN: 
9780191827877
DOI: 
10.1093/actrade/9780198786207.003.0002
Item type: 
chapter
ISBN: 
9780198786207
For all its biological importance, DNA is a fragile molecule so extracting it is a difficult process. ‘How to read the book of life’ explains the techniques required to sequence DNA. It ... More
4. The human genome in biology and medicine

4. The human genome in biology and medicine  

John Archibald

in Genomics: A Very Short Introduction

Print Publication Year: 
Mar 2018
Published Online: 
Mar 2018
eISBN: 
9780191827877
DOI: 
10.1093/actrade/9780198786207.003.0004
Item type: 
chapter
ISBN: 
9780198786207
The initial phase of human genome sequencing is often referred to as ‘the’ Human Genome Project. But there were two different projects, one publicly funded, the other supported by a private ... More
3. Making sense of genes and genomes

3. Making sense of genes and genomes  

John Archibald

in Genomics: A Very Short Introduction

Print Publication Year: 
Mar 2018
Published Online: 
Mar 2018
eISBN: 
9780191827877
DOI: 
10.1093/actrade/9780198786207.003.0003
Item type: 
chapter
ISBN: 
9780198786207
While DNA sequencing is faster and cheaper than ever before, genome assembly remains a significant challenge. ‘Making sense of genes and genomes’ explores how laboratory and computational ... More
6. Molecules and men

6. Molecules and men  

John Waller

in Heredity: A Very Short Introduction

Print Publication Year: 
Aug 2017
Published Online: 
Aug 2017
eISBN: 
9780191831706
DOI: 
10.1093/actrade/9780198790457.003.0006
Item type: 
chapter
ISBN: 
9780198790457
‘Molecules and men’ describes the brilliance, ingenuity, and ugliness with which ideas about heredity were developed and deployed from 1900 into the 1960s. Within sixty years the new field ... More

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