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p. 724. Schizophrenia and drugslocked

  • Christopher Frith
  •  and Eve Johnstone


According to ‘Schizophrenia and drugs’, one of the most exciting scientific developments in the second half of the twentieth century concerned the discovery of the role of chemical messengers (neurotransmitters) in the brain and their importance for understanding how drugs work. In parallel with these discoveries, a number of drugs were identified that have a direct effect on many of the symptoms associated with schizophrenia, by blocking dopamine receptors in the brain. Though these reduce hallucinations and delusions, we are still a long way from a cure. The drugs currently available often have unpleasant side-effects, and there are a few patients for whom no suitable pharmacological treatment can be found.

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