Show Summary Details

p. 757. Persistent viruseslocked

  • Dorothy H. Crawford


‘Persistent viruses’ explains how some viruses have evolved strategies for overcoming immune mechanisms and survive inside their host for prolonged periods, even for a lifetime. Evasion strategies encompass three basic manoeuvres: finding a niche in which to hide from immune attack, manipulating immune processes to benefit the virus, and outwitting immune defences by mutating rapidly. Most persistent viruses have evolved to cause mild or even asymptomatic infections, since a life-threatening disease would not only be detrimental to the host, but would also deprive the virus of its home. The herpesvirus family, retrovirus family, HIV-1, and hepatitis viruses are described in detail.

Access to the complete content on Very Short Introductions online requires a subscription or purchase. Public users are able to search the site and view the abstracts and keywords for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.