What was the Scientific Revolution and when was it? The Introduction states that it started around 1500 and ended around 1700 and it is the most important and talked-about era in the history of science. Some see it as a break from the medieval world. Others see it as an illusion of retrospection. The period saw a substantial increase in the number of people asking questions about the natural world, a proliferation of new answers, and the development of new methods for getting answers. The Scientific Revolution laid many of the foundations that continue to underpin modern scientific methods and knowledge.