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p. 11311. Evolutionlocked

  • Lewis Wolpert

Abstract

‘Evolution’ shows that development is a fundamental process in the evolution of multicellular organisms. The evolution of multicellular forms of all animals and plants is the result of changes in embryonic development and these, in turn, are entirely due to changes in genes that control cell behaviour in the embryo and adult. Changes in the regulation of gene expression in time and space, and mutations in proteins that generate novel protein functions, have both played a fundamental role in evolution. Genetically based changes in development that generated more successful adult forms better adapted to their environment and so able to reproduce better, have been selected for during evolution.

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